Pimobendan versus benazepril in dogs with mitral valve disease and congestive heart failure

Clinical Scenario

Barney is a 7-year-old male neutered Cavalier King Charles Spaniel who presented to you with a cough and a heart murmur during morning surgery. He is in good body condition, but has lost 1 kg in weight since you saw him last year. You have radiographed his thorax, and he has both cardiomegaly and pulmonary oedema. Echocardiography reveals marked mitral valve disease.

His owner is very worried about Barney and has limited money to spend on treatment, but wants to know how long Barney will live and also wants him to have the best treatment possible. You have pimobendan and benazepril available to you on the shelf, and wonder which drug will maximise Barney’s survival time.

PICO question

Reveal example question

Full example