O – Outcome

What can I hope to accomplish or measure?

Finally, any decision between two choices rests on an outcome of interest.

A non-clinical example is solving a problem of choosing a car. If your desired outcome is economy, a fast, flashy sports car might be a terrible solution, whereas if your desired outcome is top speed, that sports car would be ideal.

Choosing a specific desired outcome is a key part of the personalisation that EBVM gives, allowing you to seek evidence, APPRAISE it, and act with a specific outcome or objective in mind that is directly tailored to your individual patient.

For instance, in the case of a geriatric cat with chronic renal disease, you may decide that your desired outcome will be quality of life rather than overall duration of survival.

Question Outcome
Which diet is best to feed cats with chronic renal disease? Survival time
Which diagnostic test is most reliable for diagnosing fascioliasis in dairy cattle? Better sensitivity and specificity for diagnosing fascioliasis
Does sex affect survival in flat-coat retrievers with cancer? Average life expectancy
What are the risks of general anaesthesia in ferrets? An increased risk of death
What is the prevalence of cardiac disorders in Welsh Section A mountain ponies? Prevalence of cardiac disorders